Reticuloendothelial System Activity and Organ Failure in Patients With Multiple Injuries

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Reticuloendothelial system activity and organ failure in patients with multiple injuries.

HYPOTHESIS Reticuloendothelial system function is altered in patients with multiple trauma and organ failure. DESIGN Prospective cohort study. SETTING Surgical intensive care unit at a level I trauma center. PATIENTS Patients with multiple blunt trauma and injury severity scores greater than 20, with no referrals. INTERVENTIONS Every second day reticuloendothelial system (RES) clearance...

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Multiple organ failure (MOF) is the main cause of death in ICUs, especially affecting septic patients. It is strongly related to number of systems with failure, type of system involved, risk factors such as age, previous chronic diseases, delayed or inadequate resuscitation, persistent infection, immune suppression, and others. The prognoses is worse for patients rather than in elective or emer...

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Multiple Organ Failure in Elderly Patients with Chronic Diseases

Multiple organ failure (MOFE) in elderly patients is a new clinical syndrome different from multiple organ failure (MOF) caused by surgical conditions in the young and middle-aged persons. One thousand and two cases of MOFE were analyzed retrospectively and their clinical features discussed. MOFE has a long insidious course. Its main predisposing factors are pulmonary infection, heart attack, e...

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Reticuloendothelial system and hepatocytic function in fulminant hepatic failure.

Kupffer cell and hepatocyte function were studied in 36 patients with fulminant hepatic failure by measurement of clearance of 125I microaggregated albumin (125IMAA) and galactose, respectively. Both were impaired but there was no correlation with final outcome, although on sequential testing 48 hours later, those patients who survived had a significantly greater improvement in Kupffer cell and...

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ژورنال

عنوان ژورنال: Archives of Surgery

سال: 1999

ISSN: 0004-0010

DOI: 10.1001/archsurg.134.4.421